What is Focal Segmental Glomerulosclerosis (FSGS)?
Focal Segmental Glomerulosclerosis (FSGS) is a rare disease that attacks the kidney's filtering system (glomeruli) causing serious scarring. FSGS is one of the causes of a serious condition known as Nephrotic Syndromefeatured by Proteinuria, edema, hypoproteinemia and hyperlipemia.
What does Focal Segmental Glomerulosclerosis (FSGS) mean?
Sclerosis means "scarring to the filters of kidneys, glomeruli". The word "focal" is added because in FSGS, only some of the glomeruli become scarred. "Segmental" means that only some sections of the glomerulus becomes scarred, just parts of them.
So Focal Segmental Glomerulosclerosis means:
Focal = some
Segmental = sections
Glomerulo = of kidney filters (glomeruli)
Sclerosis = are scarred
The prognosis of Focal Segmental Glomerulosclerosis(FSGS) is poor. It is indicated by data that for patients with FSGS, the 5-year survival rate of kidneys is 70%, while the 10-year survival rate is 40%.
For Focal Segmental Glomerulosclerosis(FSGS) patients who can remit completely by treatment, the condition is stable; on the other hand, for FSGS patients who can not remit, the kidney function will worsen constantly, and most of the patients(30%~63%) will develop into Kidney Failure.
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